APkNUCdi_DNA: Amphiphilic Pseudo-k Nucleotide Composition-di(series)...
In ftrCOOL: Feature Extraction from Biological Sequences

Description Usage Arguments Details Value Examples

This function calculates the amphiphilic pseudo k nucleotide composition(Di) (Series) for each sequence.

APkNUCdi_DNA(
  seqs,
  selectedIdx = c("Rise", "Roll", "Shift", "Slide", "Tilt", "Twist"),
  lambda = 3,
  w = 0.05,
  l = 2,
  ORF = FALSE,
  reverseORF = TRUE,
  threshold = 1,
  label = c()
)

`seqs`	is a FASTA file containing nucleotide sequences. The sequences start with '>'. Also, seqs could be a string vector. Each element of the vector is a nucleotide sequence.
`selectedIdx`	is a vector of Ids or indices of the desired physicochemical properties of dinucleotides. Users can choose the desired indices by their ids or their names in the DI_DNA index file. The default value of this parameter is a vector with ("Rise", "Roll", "Shift", "Slide", "Tilt", "Twist") ids.
`lambda`	is a tuning parameter. This integer value shows the maximum limit of spaces between dinucleotide pairs. The Number of spaces changes from 1 to lambda.
`w`	(weight) is a tuning parameter. It changes in the range of 0 to 1. The default value is 0.05.
`l`	This parameter keeps the value of l in lmer composition. The lmers form the first 4^l elements of the APkNCdi descriptor.
`ORF`	(Open Reading Frame) is a logical parameter. If it is set to true, ORF region of each sequence is considered instead of the original sequence (i.e., 3-frame).
`reverseORF`	is a logical parameter. It is enabled only if ORF is true. If reverseORF is true, ORF region will be searched in the sequence and also in the reverse complement of the sequence (i.e., 6-frame).
`threshold`	is a number between (0 to 1]. In selectedIdx, indices with a correlation higher than the threshold will be deleted. The default value is 1.
`label`	is an optional parameter. It is a vector whose length is equivalent to the number of sequences. It shows the class of each entry (i.e., sequence).

This function computes the pseudo nucleotide composition for each physicochemical property of dinucleotides. We have provided users with the ability to choose among the 148 properties in the di-nucleotide index database.

It is a feature matrix. The number of columns is 4^l+(number of the chosen indices*lambda) and the number of rows is equal to the number of sequences.