TTN: TTN data set

In gaston: Genetic Data Handling (QC, GRM, LD, PCA) & Linear Mixed Models

TTN data set

Description

These data have been extracted from the 1000 Genomes data. The data set contains the genotype matrix TTN.gen, the pedigree matrix TTN.fam and a matrix TTN.bim, corresponding to 503 individuals of European populations and 733 SNPs on chromosome 2, on a ~600kb segment containing the Titin gene. There is also a factor TTN.pop, which gives the population from which each individual is drawn (CEU = Utah residents of Northern Western European ancestry, FIN = Finnish, GBR = England and Scottland, IBS = Iberian, TSI = Toscani).

Usage

 data(TTN) 

Format

There are three data objects in the dataset:

TTN.gen

Genotype matrix

TTN.fam

Data frame containing all variables corresponding to a .fam file

TTN.bim

Data frame containing all variables corresponding to a .bim file

TTN.pop

Factor giving the population from which each individual is drawn

Source

The data were obtained from the 1000 Genomes project (see https://www.internationalgenome.org/).

References

McVean et al, 2012, An integrated map of genetic variation from 1,092 human genomes, Nature 491, 56-65 doi:10.1038/nature11632

Examples

data(TTN)
x <- as.bed.matrix(TTN.gen, TTN.fam, TTN.bim)
x

gaston documentation built on Dec. 28, 2022, 1:30 a.m.