grandR: Comprehensive Analysis of Nucleotide Conversion Sequencing Data

Nucleotide conversion sequencing experiments have been developed to add a temporal dimension to RNA-seq and single-cell RNA-seq. Such experiments require specialized tools for primary processing such as GRAND-SLAM, (see 'Jürges et al' <doi:10.1093/bioinformatics/bty256>) and specialized tools for downstream analyses. 'grandR' provides a comprehensive toolbox for quality control, kinetic modeling, differential gene expression analysis and visualization of such data. Fast Wilcoxon tests are supported via the 'presto' package (available at <https://github.com/immunogenomics/presto>).

Package details

AuthorFlorian Erhard [aut, cre] (ORCID: <https://orcid.org/0000-0002-3574-6983>), Teresa Rummel [ctb], Julian Selke [ctb]
MaintainerFlorian Erhard <Florian.Erhard@informatik.uni-regensburg.de>
LicenseApache License (>= 2)
Version0.2.7
URL https://github.com/erhard-lab/grandR
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("grandR")

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grandR documentation built on Jan. 14, 2026, 5:08 p.m.