hla.demo: HLA Loci and Serologic Response to Measles Vaccination

In haplo.stats: Statistical Analysis of Haplotypes with Traits and Covariates when Linkage Phase is Ambiguous

HLA Loci and Serologic Response to Measles Vaccination

Description

A data frame with genotypes at eleven HLA-region loci genotyped for 220 subjects, phase not known. Contains measles vaccination response with covariate data.

Usage

data(hla.demo)

Format

A data frame with 220 observations on the following 26 variables.

resp

numeric, Quantitative response to Measles Vaccination

resp.cat

Category of vaccination response, a factor with levels high low normal

male

numeric, indicator of gener, 1=male, 0=female

age

numeric, subject's age

DPB.a1

first allele of genotype

DPB.a2

second allele of genotype

DPA.a1

first allele of genotype

DPA.a2

second allele of genotype

DMA.a1

first allele of genotype

DMA.a2

second allele of genotype

DMB.a1

first allele of genotype

DMB.a2

second allele of genotype

TAP1.a1

first allele of genotype

TAP1.a2

second allele of genotype

TAP2.a1

first allele of genotype

TAP2.a2

second allele of genotype

DQB.a1

first allele of genotype

DQB.a2

second allele of genotype

DQA.a1

first allele of genotype

DQA.a2

second allele of genotype

DRB.a1

first allele of genotype

DRB.a2

second allele of genotype

B.a1

first allele of genotype

B.a2

second allele of genotype

A.a1

first allele of genotype

A.a2

second allele of genotype

Source

Data set kindly provided by Gregory A. Poland, M.D. and the Mayo Clinic Vaccine Research Group for illustration only, and my not be used for publication.

References

Schaid DJ, Rowland CM, Tines DE, Jacobson RM, Poland GA. "Score tests for association of traits with haplotypes when linkage phase is ambiguous." Amer J Hum Genet. 70 (2002): 425-434.

Examples

data(hla.demo)

haplo.stats documentation built on May 29, 2024, 9:53 a.m.