IWP: Calculates patient-level individual win proportions

In hce: Design and Analysis of Hierarchical Composite Endpoints

Calculates patient-level individual win proportions

Description

Calculates patient-level individual win proportions

Usage

IWP(data, AVAL, TRTP, ref)

Arguments

data	a data frame containing subject-level data.
AVAL	variable in the data with ordinal analysis values.
TRTP	the treatment variable in the data.
ref	the reference treatment group.

Value

the input data frame with a new column of individual win proportions named using the input AVAL value with ⁠_⁠.

References

Gasparyan SB et al. "Adjusted win ratio with stratification: calculation methods and interpretation." Statistical Methods in Medical Research 30.2 (2021): 580-611. doi:10.1177/0962280220942558

See Also

calcWO(), calcWO.hce(), calcWO.formula().

Examples

KHCE1 <- IWP(data = KHCE, AVAL = "EGFRBL", TRTP = "TRTPN", ref = 2)
WP <- tapply(KHCE1$EGFRBL_, KHCE1$TRTPN, mean)
VAR <- tapply(KHCE1$EGFRBL_, KHCE1$TRTPN, function(x) (length(x)-1)*var(x)/length(x))
N <- tapply(KHCE1$EGFRBL_, KHCE1$TRTPN, length)
SE <- sqrt(sum(VAR/N))
c(WP = WP[[1]], SE = SE)
calcWO(EGFRBL ~ TRTP, data = KHCE)[c("WP", "SE_WP")]

hce documentation built on April 3, 2025, 11:17 p.m.