Nothing
#' Posterior of power prior (PP) with fixed \eqn{a_0}
#'
#' Sample from the posterior distribution of a piecewise exponential (PWE) model (i.e., a proportional hazards model
#' with a piecewise constant baseline hazard) using the power prior (PP) by Ibrahim and Chen (2000)
#' <doi:10.1214/ss/1009212673>.
#'
#' The power prior parameters (\eqn{a_0}'s) are treated as fixed. The initial priors on the regression coefficients
#' are independent normal priors. The current and historical data models are assumed to share the baseline hazard
#' parameters with half-normal priors.
#'
#' @include data_checks_pwe.R
#' @include get_stan_data_pwe.R
#'
#' @export
#'
#' @param formula a two-sided formula giving the relationship between the response variable and covariates.
#' The response is a survival object as returned by the `survival::Surv(time, event)` function,
#' where event is a binary indicator for event (0 = no event, 1 = event has occurred). The type of
#' censoring is assumed to be right-censoring.
#' @param data.list a list of `data.frame`s. The first element in the list is the current data, and the rest
#' are the historical data sets. For fitting piecewise exponential (PWE) models, all historical
#' data sets will be stacked into one historical data set.
#' @param breaks a numeric vector specifying the time points that define the boundaries of the piecewise
#' intervals. The values should be in ascending order, with the final value being greater than
#' or equal to the maximum observed time.
#' @param a0 a scalar between 0 and 1 giving the (fixed) power prior parameter for the historical data.
#' @param beta.mean a scalar or a vector whose dimension is equal to the number of regression coefficients giving
#' the mean parameters for the initial prior on regression coefficients. If a scalar is provided,
#' `beta.mean` will be a vector of repeated elements of the given scalar. Defaults to a vector of 0s.
#' @param beta.sd a scalar or a vector whose dimension is equal to the number of regression coefficients giving
#' the sd parameters for the initial prior on regression coefficients. If a scalar is provided,
#' same as for `beta.mean`. Defaults to a vector of 10s.
#' @param base.hazard.mean a scalar or a vector whose dimension is equal to the number of intervals giving the location
#' parameters for the half-normal priors on the baseline hazards of the PWE model. If a scalar is
#' provided, same as for `beta.mean`. Defaults to 0.
#' @param base.hazard.sd a scalar or a vector whose dimension is equal to the number of intervals giving the scale
#' parameters for the half-normal priors on the baseline hazards of the PWE model. If a scalar is
#' provided, same as for `beta.mean`. Defaults to 10.
#' @param get.loglik whether to generate log-likelihood matrix. Defaults to FALSE.
#' @param iter_warmup number of warmup iterations to run per chain. Defaults to 1000. See the argument `iter_warmup` in
#' `sample()` method in cmdstanr package.
#' @param iter_sampling number of post-warmup iterations to run per chain. Defaults to 1000. See the argument `iter_sampling`
#' in `sample()` method in cmdstanr package.
#' @param chains number of Markov chains to run. Defaults to 4. See the argument `chains` in `sample()` method in
#' cmdstanr package.
#' @param ... arguments passed to `sample()` method in cmdstanr package (e.g., `seed`, `refresh`, `init`).
#'
#' @return
#' The function returns an object of class `draws_df` containing posterior samples. The object has two attributes:
#'
#' \describe{
#' \item{data}{a list of variables specified in the data block of the Stan program}
#'
#' \item{model}{a character string indicating the model name}
#' }
#'
#' @references
#' Chen, M.-H. and Ibrahim, J. G. (2000). Power prior distributions for Regression Models. Statistical Science, 15(1).
#'
#' @examples
#' if (instantiate::stan_cmdstan_exists()) {
#' if(requireNamespace("survival")){
#' library(survival)
#' data(E1684)
#' data(E1690)
#' ## take subset for speed purposes
#' E1684 = E1684[1:100, ]
#' E1690 = E1690[1:50, ]
#' ## replace 0 failure times with 0.50 days
#' E1684$failtime[E1684$failtime == 0] = 0.50/365.25
#' E1690$failtime[E1690$failtime == 0] = 0.50/365.25
#' E1684$cage = as.numeric(scale(E1684$age))
#' E1690$cage = as.numeric(scale(E1690$age))
#' data_list = list(currdata = E1690, histdata = E1684)
#' nbreaks = 3
#' probs = 1:nbreaks / nbreaks
#' breaks = as.numeric(
#' quantile(E1690[E1690$failcens==1, ]$failtime, probs = probs)
#' )
#' breaks = c(0, breaks)
#' breaks[length(breaks)] = max(10000, 1000 * breaks[length(breaks)])
#' pwe.pp(
#' formula = survival::Surv(failtime, failcens) ~ treatment + sex + cage + node_bin,
#' data.list = data_list,
#' breaks = breaks,
#' a0 = 0.5,
#' chains = 1, iter_warmup = 500, iter_sampling = 1000
#' )
#' }
#' }
pwe.pp = function(
formula,
data.list,
breaks,
a0,
beta.mean = NULL,
beta.sd = NULL,
base.hazard.mean = NULL,
base.hazard.sd = NULL,
get.loglik = FALSE,
iter_warmup = 1000,
iter_sampling = 1000,
chains = 4,
...
) {
## get Stan data for PP
standat = get.pwe.stan.data.pp(
formula = formula,
data.list = data.list,
breaks = breaks,
a0 = a0,
beta.mean = beta.mean,
beta.sd = beta.sd,
base.hazard.mean = base.hazard.mean,
base.hazard.sd = base.hazard.sd,
get.loglik = get.loglik
)
pwe_pp = instantiate::stan_package_model(
name = "pwe_pp",
package = "hdbayes"
)
## fit model in cmdstanr
fit = pwe_pp$sample(data = standat,
iter_warmup = iter_warmup, iter_sampling = iter_sampling, chains = chains,
...)
## rename parameters
p = standat$p
X1 = standat$X1
J = standat$J
if( p > 0 ){
oldnames = c(paste0("beta[", 1:p, "]"), paste0("lambda[", 1:J, "]"))
newnames = c(colnames(X1), paste0("basehaz[", 1:J, "]"))
}else{
oldnames = paste0("lambda[", 1:J, "]")
newnames = paste0("basehaz[", 1:J, "]")
}
d = rename.params(fit = fit, oldnames = oldnames, newnames = newnames)
## add data used for the variables specified in the data block of the Stan program as an attribute
attr(x = d, which = 'data') = standat
## add model name as an attribute
attr(x = d, which = 'model') = "pwe_pp"
return(d)
}
Any scripts or data that you put into this service are public.
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.