iC10TrainingData-package: Training Datasets for iC10 Package

Description Details Author(s) References See Also Examples

Description

Training datasets for iC10; which implements the classifier described in the paper 'Genome-driven integrated classification of breast cancer validated in over 7,500 samples' (Ali HR et al., Genome Biology 2014). It uses copy number and/or expression form breast cancer data, trains a pamr classifier (Tibshirani et al.) with the features available and predicts the iC10 group. Genomic annotation for the training dataset has been obtained from Mark Dunning's lluminaHumanv3.db package. Training datasets for iC10; which implements the classifier described in the METABRIC paper 'The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups' (Curtis et al., Nature 2012). It uses copy number and/or expression form breast cancer data, trains a pamr classifier (Tibshirani et al.) with the features available and predicts the iC10 group.

Details

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Training datasets for iC10; which implements the classifier described in the METABRIC paper 'The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups' (Curtis et al., Nature 2012). It uses copy number and/or expression form breast cancer data, trains a pamr classifier (Tibshirani et al.) with the features available and predicts the iC10 group.

Author(s)

Oscar M Rueda and Jose Antonio Seoane Fernandez

Maintainer: Oscar M. Rueda <[email protected]>

References

Curtis et al. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature 2012; 486:346-352. Tibshirani et al. Diagnosis of multiple cancer types by shrunken centroids of gene expression. PNAS 2002; 99(10):6567-6572.

See Also

iC10

Examples

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iC10TrainingData documentation built on Aug. 24, 2018, 5:04 p.m.