ibdsim2-package: ibdsim2: Simulation of Chromosomal Regions Shared by Family...

In ibdsim2: Simulation of Chromosomal Regions Shared by Family Members

ibdsim2: Simulation of Chromosomal Regions Shared by Family Members

Description

Simulation of segments shared identical-by-descent (IBD) by pedigree members. Using sex specific recombination rates along the human genome (Halldorsson et al. (2019) \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1126/science.aau1043")}), phased chromosomes are simulated for all pedigree members. Applications include calculation of realised relatedness coefficients and IBD segment distributions. 'ibdsim2' is part of the 'ped suite' collection of packages for pedigree analysis. A detailed presentation of the 'ped suite', including a separate chapter on 'ibdsim2', is available in the book 'Pedigree analysis in R' (Vigeland, 2021, ISBN:9780128244302). A 'shiny' app for visualising and comparing IBD distributions is available at https://magnusdv.shinyapps.io/ibdsim2-shiny/.

Author(s)

Maintainer: Magnus Dehli Vigeland [e-mail] (ORCID)

See Also

Useful links:

• https://github.com/magnusdv/ibdsim2

• https://magnusdv.github.io/pedsuite/

• https://magnusdv.shinyapps.io/ibdsim2-shiny/

ibdsim2 documentation built on Aug. 17, 2023, 5:17 p.m.