imputeLCMD: A Collection of Methods for Left-Censored Missing Data Imputation

A collection of functions for left-censored missing data imputation. Left-censoring is a special case of missing not at random (MNAR) mechanism that generates non-responses in proteomics experiments. The package also contains functions to artificially generate peptide/protein expression data (log-transformed) as random draws from a multivariate Gaussian distribution as well as a function to generate missing data (both randomly and non-randomly). For comparison reasons, the package also contains several wrapper functions for the imputation of non-responses that are missing at random. * New functionality has been added: a hybrid method that allows the imputation of missing values in a more complex scenario where the missing data are both MAR and MNAR.

Getting started

Package details

AuthorCosmin Lazar [aut], Thomas Burger [aut], Samuel Wieczorek [cre, ctb]
MaintainerSamuel Wieczorek <>
LicenseGPL (>= 2)
Package repositoryView on CRAN
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imputeLCMD documentation built on June 10, 2022, 5:09 p.m.