The package contains a collection of functions for leftcensored missing data imputation. Leftcensoring is a special case of missing not at random (MNAR) mechanism that generates nonresponses in proteomics experiments. The package also contains functions to artificially generate peptide/protein expression data (logtransformed) as random draws from a multivariate Gaussian distribution as well as a function to generate missing data (both randomly and nonrandomly). For comparison reasons, the package also contains several wrapper functions for the imputation of nonresponses that are missing at random. * New functionality has been added: a hybrid method that allows the imputation of missing values in a more complex scenario where the missing data are both MAR and MNAR.
Package details 


Author  Cosmin Lazar 
Date of publication  20150119 07:09:10 
Maintainer  Cosmin Lazar <[email protected]> 
License  GPL (>= 2) 
Version  2.0 
Package repository  View on CRAN 
Installation 
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