powerRiskDiffExactEquiv: Power for exact unconditional test of equivalence in risk...

In lrstat: Power and Sample Size Calculation for Non-Proportional Hazards and Beyond

Power for exact unconditional test of equivalence in risk difference

Description

Obtains the power given sample size for exact unconditional test of equivalence in risk difference.

Usage

powerRiskDiffExactEquiv(
  n = NA_integer_,
  riskDiffLower = NA_real_,
  riskDiffUpper = NA_real_,
  pi1 = NA_real_,
  pi2 = NA_real_,
  allocationRatioPlanned = 1,
  alpha = 0.05,
  calculateAttainedAlpha = 1L
)

Arguments

n	The total sample size.
riskDiffLower	The lower equivalence limit of risk difference.
riskDiffUpper	The upper equivalence limit of risk difference.
pi1	The assumed probability for the active treatment group.
pi2	The assumed probability for the control group.
allocationRatioPlanned	Allocation ratio for the active treatment versus control. Defaults to 1 for equal randomization.
alpha	The significance level for each of the two one-sided tests. Defaults to 0.05.
calculateAttainedAlpha	Whether to calculate the attained alpha.

Value

A data frame with the following variables:

• alpha: The specified significance level for each of the two one-sided tests.

• attainedAlphaH10: The attained significance level under H10 if requested.

• attainedAlphaH20: The attained significance level under H20 if requested.

• power: The power.

• n: The sample size.

• riskDiffLower: The lower equivalence limit of risk difference.

• riskDiffUpper: The upper equivalence limit of risk difference.

• pi1: The assumed probability for the active treatment group.

• pi2: The assumed probability for the control group.

• riskDiff: The risk difference.

• allocationRatioPlanned: Allocation ratio for the active treatment versus control.

• zstatRiskDiffLower: The efficacy boundaries on the z-test statistic scale for the one-sided null hypothesis on the lower equivalence limit.

• zstatRiskDiffUpper: The efficacy boundaries on the z-test statistic scale for the one-sided null hypothesis on the upper equivalence limit.

Author(s)

Kaifeng Lu, [e-mail]

Examples

powerRiskDiffExactEquiv(
  n = 200, riskDiffLower = -0.2, riskDiffUpper = 0.2,
  pi1 = 0.775, pi2 = 0.775, alpha = 0.05)

lrstat documentation built on June 23, 2024, 5:06 p.m.