shilong: The randomized clinical trial SHIVA data in long format from...

shilongR Documentation

The randomized clinical trial SHIVA data in long format from the ipcwswitch package

Description

The original SHIdat data set contains an anonymized excerpt of data from the SHIVA01 trial. This was the first randomized clinical trial that aimed at comparing molecularly targeted therapy based on tumor profiling (MTA) versus conventional therapy (CT) for advanced cancer. Patients were randomly assigned to receive the active or control treatment and may switch to the other arm or subsequent anti-cancer therapy upon disease progression. The restructured data is in the long format.

id

The patient's identifier

tstart

The start of the time interval

tstop

The end of the time interval

event

Whether the patient died at the end of the interval

agerand

The patient's age (in years) at randomization

sex.f

The patients' gender, either Male or Female

tt_Lnum

The number of previous lines of treatment

rmh_alea.c

The Royal Marsden Hospital score segregated into two categories

pathway.f

The molecular pathway altered (the hormone receptors pathway, the PI3K/ AKT/mTOR pathway, and the RAF/MEK pathway)

bras.f

The patient's randomized arm, either MTA or CT

ps

The ECOG performance status

ttc

The presence of concomitant treatments

tran

The use of platelet transfusions

dpd

The relative day of a potential progression

dco

The relative day of treatment switching

ady

The relative day of the latest news

dcut

The relative day of administrative cutoff

pd

Whether the patient had disease progression

co

Whether the patient switched treatment

Usage

shilong

Format

An object of class data.frame with 602 rows and 19 columns.


lrstat documentation built on Oct. 18, 2024, 9:06 a.m.