shilong | R Documentation |
The original SHIdat data set contains an anonymized excerpt of data from the SHIVA01 trial. This was the first randomized clinical trial that aimed at comparing molecularly targeted therapy based on tumor profiling (MTA) versus conventional therapy (CT) for advanced cancer. Patients were randomly assigned to receive the active or control treatment and may switch to the other arm or subsequent anti-cancer therapy upon disease progression. The restructured data is in the long format.
id
The patient's identifier
tstart
The start of the time interval
tstop
The end of the time interval
event
Whether the patient died at the end of the interval
agerand
The patient's age (in years) at randomization
sex.f
The patients' gender, either Male or Female
tt_Lnum
The number of previous lines of treatment
rmh_alea.c
The Royal Marsden Hospital score segregated into two categories
pathway.f
The molecular pathway altered (the hormone receptors pathway, the PI3K/ AKT/mTOR pathway, and the RAF/MEK pathway)
bras.f
The patient's randomized arm, either MTA or CT
ps
The ECOG performance status
ttc
The presence of concomitant treatments
tran
The use of platelet transfusions
dpd
The relative day of a potential progression
dco
The relative day of treatment switching
ady
The relative day of the latest news
dcut
The relative day of administrative cutoff
pd
Whether the patient had disease progression
co
Whether the patient switched treatment
shilong
An object of class data.frame
with 602 rows and 19 columns.
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