Description Usage Format References
The data set presented by Mantel, et al. (1977) is based on a tumorigenesis study of 50 litters of female rats. For each litter, one rat was selected to receive the drug and the other two rats were placebo-treated controls. Here each litter is treated as a cluster. The survival time is the time to development of tumor, measured in weeks. Death before occurrence of tumor yields a right-censored observation; forty rats developed a tumor, leading to censoring of about 73 percent.
1 | data("rats")
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A data frame with 300 observations on the following 5 variables.
littercluster number for 50 litters
rxtratment (1=drug, 0=placebo)
timetime to development of tumor, measured in weeks
statusstatus (1=occurrence of event, 0=censoring)
sexa factor with levels f (female) and m (male)
Mantel, N., Bohidar, N.R. and Ciminera, J.L. (1977). Mantel-haenszel analyses of litter-matched time-to-response data, with modifications for recovery of interlitter information. Cancer Research, 37, 3863–3868.
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