Description Usage Format References
The data set presented by Mantel, et al. (1977) is based on a tumorigenesis study of 50 litters of female rats. For each litter, one rat was selected to receive the drug and the other two rats were placebo-treated controls. Here each litter is treated as a cluster. The survival time is the time to development of tumor, measured in weeks. Death before occurrence of tumor yields a right-censored observation; forty rats developed a tumor, leading to censoring of about 73 percent.
1 | data("rats")
|
A data frame with 300 observations on the following 5 variables.
litter
cluster number for 50 litters
rx
tratment (1=drug, 0=placebo)
time
time to development of tumor, measured in weeks
status
status (1=occurrence of event, 0=censoring)
sex
a factor with levels f
(female) and m
(male)
Mantel, N., Bohidar, N.R. and Ciminera, J.L. (1977). Mantel-haenszel analyses of litter-matched time-to-response data, with modifications for recovery of interlitter information. Cancer Research, 37, 3863–3868.
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