pkCurveStat: calculate summary statistics from a pkCurve

In microsamplingDesign: Finding Optimal Microsampling Designs for Non-Compartmental Pharmacokinetic Analysis

Description

implemented statistics:

• auc area under the curve , between first and last time points

• cMax maximum concentration

• tMax time at maximum concentration

Usage

pkCurveStat_auc(concentration, timePoints)

pkCurveStat_cMax(concentration, timePoints)

pkCurveStat_tMax(concentration, timePoints)

Arguments

concentration	numeric vector of concentrations corresponding to timePoints
timePoints	time and concentration

Value

a numeric value

Examples

  ## toy example
  timeToy               <-  1:2
  concToy               <-  1:2 
 
  pkCurveStat_auc( concToy ,  timeToy ) 
  pkCurveStat_cMax( concToy ,  timeToy  )
  pkCurveStat_tMax( concToy ,  timeToy  )

  ## real example
  times                 <-  c(0 , 1.5 , 2:10)
  concentration         <-  getExamplePkCurve( times )
  pkCurveStat_auc( concentration , times  ) 
  pkCurveStat_cMax( concentration , times   )
  pkCurveStat_tMax( concentration , times   )

microsamplingDesign documentation built on Oct. 13, 2021, 5:10 p.m.