Conduct multi-locus genome-wide association study under the framework of random-SNP-effect mixed linear model (mrMLM). First, each marker on the genome is scanned. Bonferroni correction is replaced by a less stringent selection criterion for significant test. Then, all the markers that are potentially associated with the trait are included in a multi-locus model, their effects are estimated by empirical Bayes and true QTN are identified by likelihood ratio test.
|Author||Zhang Ya-Wen, Li Pei, Ren Wen-Long, Ni Yuan-Li, and Zhang Yuan-Ming|
|Date of publication||2018-03-12 04:09:16 UTC|
|Maintainer||Yuanming Zhang<[email protected]>|
|License||GPL (>= 2)|
|Package repository||View on CRAN|
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