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Conduct multi-locus genome-wide association study under the framework of random-SNP-effect mixed linear model (mrMLM). First, each marker on the genome is scanned. Bonferroni correction is replaced by a less stringent selection criterion for significant test. Then, all the markers that are potentially associated with the trait are included in a multi-locus model, their effects are estimated by empirical Bayes and true QTN are identified by likelihood ratio test.
Package details |
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Author | Zhang Ya-Wen, Li Pei, Ren Wen-Long, Ni Yuan-Li, and Zhang Yuan-Ming |
Date of publication | 2018-03-12 04:09:16 UTC |
Maintainer | Yuanming Zhang<[email protected]> |
License | GPL (>= 2) |
Version | 3.0 |
Package repository | View on CRAN |
Installation |
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