mrMLM: Multi-Locus Random-SNP-Effect Mixed Linear Model for Genome-Wide Association Studies and Linkage Analyses
Version 2.1

Conduct multi-locus GWAS and multi-locus QTL mapping under the framework of random-SNP-effect mixed linear model (mrMLM). First, each position (or marker) on the genome is scanned by mrMLM algorithm. Bonferroni correction is replaced by a less stringent selection criterion for significant test. Then, all the markers (or QTL) that are potentially associated with the trait are included in a multi-locus model, their effects are estimated by empirical Bayes and true QTN or QTL are identified by likelihood ratio test.

Package details

AuthorWenlong Ren,Yuanli Ni,Shibo Wang,Yangjun Wen,Bo Huang and Yuanming Zhang
Date of publication2017-02-09 07:02:00
MaintainerYuanming Zhang<[email protected]>
LicenseGPL (>= 2)
Package repositoryView on CRAN
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mrMLM documentation built on May 30, 2017, 7:02 a.m.