convertEmax: Convert linear effect to Emax effect

In nlmixr2lib: A Model Library for 'nlmixr2'

Convert linear effect to Emax effect

Description

Convert linear effect to Emax effect

Usage

convertEmax(
  ui,
  emax = "Emax",
  ec50 = "EC50",
  imax = "Imax",
  ic50 = "IC50",
  ek = c("Ik", "Ek"),
  cc = c("Ec", "Cc")
)

Arguments

ui	rxode2 model
emax	Emax parameter
ec50	EC50 parameter
imax	Imax parameter used when input model contains "Ik" instead of "Ek"
ic50	IC50 parameter used when input model contains "Ik" instead of "Ek"
ek	simulation linear constant
cc	the concentration value

Value

Model with the linear effect converted to an Emax effect

Author(s)

Matthew L. Fidler

See Also

Other PD: addBaseline1exp(), addBaselineConst(), addBaselineExp(), addBaselineLin(), addDirectLin(), convertLogLin(), convertQuad()

Examples

readModelDb("PK_2cmt_no_depot") |>
  addIndirectLin(stim="in") |>
  convertEmax()

# When emax=1
readModelDb("PK_2cmt_no_depot") |>
  addIndirectLin(stim="in") |>
  convertEmax(emax=1)

nlmixr2lib documentation built on Oct. 7, 2024, 5:08 p.m.