dataset.s1: Supplementary Data Set 1

In pSI: Specificity Index Statistic

Description

Differentially expressed genes (up-regulated & down-regulated) in cortices of autsitic vs control subjects from human transcriptomic data. NOTE:Supplementary data (human & mouse expression sets, calculated pSI datasets, etc.) can be found in pSI.data package located at the following URL: http://genetics.wustl.edu/jdlab/psi_package/

Format

List containing two character vectors

Details

dataset.s1 is a list which contains two character vectors of differentially expressed genes. Differential expression was assessed using the SAM package (Significance Analysis of Microarrays), for FDR <.05 and fold change >1.3.

• dataset.s1$up.regulated
  Up-regulated genes (N=234)

• dataset.s1$down.regulated
  - Down-regulated genes (N=229)

Source

Voineagu I, Wang X, Johnston P, Lowe JK, Tian Y, Horvath S, et al. (2011): Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature. 474:380-384.

Examples

data(dataset.s1)

pSI documentation built on May 1, 2019, 10:28 p.m.