phase1RMD: Repeated Measurement Design for Phase I Clinical Trial
Version 1.0.8

Implements our Bayesian phase I repeated measurement design that accounts for multidimensional toxicity endpoints from multiple treatment cycles. The package also provides a novel design to account for both multidimensional toxicity endpoints and early-stage efficacy endpoints in the phase I design. For both designs, functions are provided to recommend the next dosage selection based on the data collected in the available patient cohorts and to simulate trial characteristics given design parameters. Yin, Jun, et al. (2017) .

Getting started

Package details

AuthorJun Yin, Yu Du, Sumithra Mandrekar
Date of publication2017-11-27 08:49:15 UTC
MaintainerJun Yin <[email protected]>
LicenseGPL (>= 2)
Version1.0.8
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("phase1RMD")

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phase1RMD documentation built on Nov. 27, 2017, 9:03 a.m.