plotPK: Plot concentration vs. time curve for individuals and...

In pkr: Pharmacokinetics in R

Plot concentration vs. time curve for individuals and collectively.

Description

Generates individual and superposed concentration vs. time curve and save it in pdf files.

Usage

plotPK(concData, id, Time, conc, unitTime = "hr", unitConc = "ng/mL", trt = "", 
       fit = "Linear", dose = 0, adm = "Extravascular", dur = 0, outdir = "Output")

Arguments

concData	name of data table containing time-concentration data of multiple subjects
id	column name for subject ID
Time	column name for the time
conc	column name for the concentration
unitTime	unit for the time
unitConc	unit for the concentration
trt	column name for the treatment code. This is useful for crossover study like bioequivalence trial.
fit	one of "Linear" or "Log" to indicate the way to calculate AUC
dose	administered dose. One should be careful for the unit. This can be a vector containing dose for each subject in order.
adm	one of "Bolus" or "Infusion" or "Extravascular" to indicate drug administration mode
dur	infusion duration for constant infusion, otherwise 0. This can be a vector containing values for each subject in order.
outdir	name of the folder to be used for the output files

Details

This function generates plots for individual and summary concentration vs. time curve. This function calles NCA().

Value

This function saves pdf files and tiff files in the outdir folder.

Author(s)

Jee Eun Lee <[e-mail]>

See Also

NCA

Examples

# plotPK(Theoph, "Subject", "Time", "conc", unitTime="hr", unitConc="mg/L", dose=320)
# plotPK(Indometh, "Subject", "time", "conc", unitTime="hr", unitConc="mg/L", adm="Bolus", dose=25)

pkr documentation built on June 11, 2022, 9:05 a.m.