phase1_sim: Override 'escalation:::phase1_sim' to incorporate latent...

In precautionary: Safety Diagnostics for Dose-Escalation Trial Designs

Description

Override escalation:::phase1_sim to incorporate latent toxicity tolerances

Usage

phase1_sim(
  selector_factory,
  true_prob_tox,
  sample_patient_arrivals = function(df) cohorts_of_n(n = 3, mean_time_delta = 1),
  previous_outcomes = "",
  next_dose = NULL,
  i_like_big_trials = FALSE,
  return_all_fits = FALSE
)

Arguments

selector_factory	A selector_factory object
true_prob_tox	A vector of toxicity probabilities for the doses defined in selector_factory
sample_patient_arrivals	A function implementing an arrivals process for trial enrollment
previous_outcomes	This may or may not apply in applications of package precautionary
next_dose	Undocumented
i_like_big_trials	I didn't choose this parameter name
return_all_fits	Don't do this

precautionary documentation built on Aug. 9, 2021, 9:14 a.m.