Description Usage Arguments Value Author(s)
Originally, the sampling in stats::rnorm()
(see inline comments in code)
consumed 53% of run-time in a 6-cohort VIOLA DTP. After this change, it
doesn't even show up! More importantly, the consumption is now dominated
by (at 75%) by the objective function 'f' in integrate().
1 2 3 4 5 6 7 | stop_for_excess_toxicity_empiric(
x,
tox_lim,
prob_cert,
dose = 1,
suppress_dose = TRUE
)
|
x |
A object of class |
tox_lim |
Scalar upper threshold on estimated toxicity rate |
prob_cert |
Confidence level for threshold exceedance |
dose |
Integer scalar, the dose being considered |
suppress_dose |
Logical; if TRUE the MTD is set to |
The mtd
object x, with stop decision annotated
Adapted by David C. Norris from original dtpcrm::stop_for_excess_toxicity_empiric
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.