statin42: FDA statin dataset with 42 adverse events

In pvEBayes: Empirical Bayes Methods for Pharmacovigilance

FDA statin dataset with 42 adverse events

Description

An adverse event-drug count dataset (contingency table) obtained from the FDA FAERS database for the quarters 2014Q3 - 2020Q4.

Usage

statin42

Format

An object of class matrix (inherits from array) with 43 rows and 7 columns.

Details

Data are stored in the form of a contingency table, with drugs listed across the columns and the 42 AEs presented across the rows. Each cell in the contingency table represents the total report counts associated with that (AE, drug) pair and detected in the FDA FAERS database during 2014Q3 - 2020Q4.

The dataset catalogs 6 statin drugs (across columns):

Atorvastatin, Fluvastatin, Lovastatin, Pravastatin, Rosuvastatin, Simvastatin.

This dataset is derived from the statin46 dataset in the pvLRT package, with four AEs removed.

The excluded AEs are: "Blood Creatine Phosphokinase Mm Increased", "Myoglobin Blood Present", "Myoglobin Urine Present", and "Myoglobinaemia".

Source

https://fis.fda.gov/extensions/FPD-QDE-FAERS/FPD-QDE-FAERS.html

pvEBayes documentation built on Aug. 8, 2025, 6:13 p.m.