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Computes noncompartmental pharmacokinetic parameters for drug concentration profiles. For each profile, data imputations and adjustments are made as necessary and basic parameters are estimated. Supports single dose, multi-dose, and multi-subject data. Supports steady-state calculations and various routes of drug administration. See ?qpNCA and vignettes. Methodology follows Rowland and Tozer (2011, ISBN:978-0-683-07404-8), Gabrielsson and Weiner (1997, ISBN:978-91-9765-100-4), and Gibaldi and Perrier (1982, ISBN:978-0824710422).
Package details |
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Author | Jan Huisman [aut, cre], Koen Jolling [ctb], Krina Mehta [ctb], Tim Bergsma [ctb] |
Maintainer | Jan Huisman <jan.huisman@qpharmetra.com> |
License | GPL-3 |
Version | 1.1.6 |
Package repository | View on CRAN |
Installation |
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