plot_reg: Plot Regression Curves

In qpNCA: Noncompartmental Pharmacokinetic Analysis by qPharmetra

Description

Plots regression curves for each set of records defined using by. A log-linear plot will be made for each curve.

Usage

plot_reg(
  x,
  by = character(0),
  th = NA,
  bloqvar = "bloq",
  timevar = "tad",
  depvar = "dv",
  timelab = "timevar",
  deplab = "depvar",
  exclvar = NA,
  plotdir = NA,
  ...
)

Arguments

x	input dataset name
by	column names in x indicating grouping variables
th	file name of file with half-life estimation information for each curve
bloqvar	variable name containing the BLOQ flag (0: no, 1: yes)
timevar	variable name containing the actual sampling time after dose
depvar	variable name containing the dependent variable (e.g., concentration)
timelab	X-axis label (default: "timevar")
deplab	Y-axis label (default: "depvar")
exclvar	variable name containing information about points to be excluded (these should have exclvar = 1)
plotdir	directory where individual plot files will be saved
...	ignored

Details

If elimination half-life was estimated for that curve, the following will be indicated in the plot:

• Cmax (Yellow, even if no half-life was estimated)

• points used in regression and resulting regression line (green)

• points excluded from regression (red crossed)

• estimate of elimination half-life and adjusted R-squared

Input dataset:

• uncorrected dataset, used for half-life estimation

• dataset containing results of the half-life estimation

Value

(invisible) plotdir. If the attribute 'plotdir' is empty, plots will be generated in standard output, otherwise plots will be saved as PNG file in the designated directory.

Examples

example(est.thalf)
x %>% filter(dv > 0) %>% plot_reg(by = 'subject', th = th)

qpNCA documentation built on Aug. 16, 2021, 5:08 p.m.