Description Usage Arguments Value
Checks whether all function arguments are valid and entered column names are present in input data
See qpNCA
for description of the arguments
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 | check.input(
x,
by = NA,
nomtimevar = NA,
timevar = NA,
depvar = NA,
bloqvar = NA,
loqvar = NA,
loqrule = NA,
includeCmax = NA,
exclvar = NA,
plotdir = NA,
timelab = NA,
deplab = NA,
tau = NA,
tstart = NA,
tend = NA,
teval = NA,
covariates = NA,
dose = NA,
factor = NA,
reg = NA,
ss = NA,
route = NA,
method = NA
)
|
x |
data.frame |
by |
column names in x indicating grouping variables |
nomtimevar |
variable name containing the nominal sampling time after dose |
timevar |
variable name containing the actual sampling time after dose |
depvar |
variable name containing the dependent variable (e.g., concentration) |
bloqvar |
variable name containing the BLOQ flag (0: no, 1: yes) |
loqvar |
variable name containing the LOQ value |
loqrule |
rule number to be applied to the LOQ values in the curve; x$loqrule overrides if provided |
includeCmax |
include Cmax in half-life estimation? (y/n); x$includeCmax overrides if provided |
exclvar |
variable name indicating points to be excluded in half-life estimation (these should have exclvar = 1) |
plotdir |
directory where regression plots (.PNG) will be saved; NA gives default location, NULL skips regression plots |
timelab |
label for time axis in regression plots |
deplab |
label for dependent variable axis in regression plots |
tau |
dosing interval (for multiple dosing); NA (default) if single dose; x$tau overrides |
tstart |
start time of partial AUC (start>0); NA (default) if not requested; x$tstart overrides |
tend |
end time of partial AUC; NA (default) if not requested; x$tend overrides |
teval |
user selected AUC interval (starting at t=0); NA (default) if not requested; x$teval overrides |
covariates |
covariates dataset; Must contain the dose variable |
dose |
variable containing the dose amount |
factor |
conversion factor for CL and V calculation (e.g. dose in mg, conc in ng/mL, factor=1000); x$factor overrides if provided |
reg |
regimen, "SD" or "MD"; x$reg overrides if provided |
ss |
is steady state reached (y/n); x$ss overrides if provided |
route |
route of drug administration ("EV","IVB", "IVI"); x$route overrides if provided |
method |
method for trapezoidal rule; x$method overrides if provided |
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