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replicateBE: Average Bioequivalence with Expanding Limits (ABEL)
Performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' / 'Method B' and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (South Africa: Cmax) - is implemented as well.
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Package details |
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| Author | Helmut Schütz [aut, cre] (<https://orcid.org/0000-0002-1167-7880>), Michael Tomashevskiy [ctb], Detlew Labes [ctb] (<https://orcid.org/0000-0003-2169-426X>) |
| Maintainer | Helmut Schütz <helmut.schuetz@bebac.at> |
| License | GPL (>= 3) |
| Version | 1.1.3 |
| URL | https://github.com/Helmut01/replicateBE |
| Package repository | View on CRAN |
| Installation |
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