PiecewiseSurvivalTime: Piecewise Exponential Survival Time
In rpact: Confirmatory Adaptive Clinical Trial Design and Analysis

PiecewiseSurvivalTime

R Documentation

Piecewise Exponential Survival Time

Class for the definition of piecewise survival times.

PiecewiseSurvivalTime is a class for the definition of piecewise survival times.

piecewiseSurvivalTime: The time intervals for the piecewise definition of the exponential survival time cumulative distribution function. Is a numeric vector.
lambda1: The assumed hazard rate in the treatment group. Is a numeric vector of length kMax.
lambda2: The assumed hazard rate in the reference group. Is a numeric vector of length 1.
hazardRatio: The hazard ratios under consideration. Is a numeric vector of length kMax.
pi1: The assumed event rate in the treatment group. Is a numeric vector of length kMax containing values between 0 and 1.
pi2: The assumed event rate in the control group. Is a numeric vector of length 1 containing a value between 0 and 1.
median1: The assumed median survival time in the treatment group. Is a numeric vector.
median2: The assumed median survival time in the reference group. Is a numeric vector of length 1.
eventTime: The assumed time under which the event rates are calculated. Is a numeric vector of length 1.
kappa: The shape of the Weibull distribution if kappa!=1. Is a numeric vector of length 1.
piecewiseSurvivalEnabled: Indicates whether specification of piecewise definition of survival time is selected. Is a logical vector of length 1.
delayedResponseAllowed: If TRUE, delayed response is allowed, if FALSE the response is not delayed.
delayedResponseEnabled: If TRUE, delayed response is enabled, if FALSE delayed response is not enabled.