ORmn: Odds Ratio and Score CI of two groups with strata by MN...

View source: R/ORmn.R

ORmnR Documentation

Odds Ratio and Score CI of two groups with strata by MN method

Description

Odds ratio and its score confidence interval of two groups with stratification by Miettinen and Nurminen method

Usage

  ORmn(d0, conf.level=0.95, eps=1e-8)

Arguments

d0

A data.frame or matrix, of which each row means a strata. This should have four columns named y1, n1, y2, and n2; y1 and y2 for events of each group, n1 and n2 for sample size of each strata. The second group is usually the control group.

conf.level

confidence level

eps

absolute value less than eps is regarded as 0

Details

It calculates odds ratio and its score confidence interval of two groups. The confidence interval is asymmetric and there is no standard error in the output. This supports stratification. This implementation uses nlminb minimization function which usually gives about 7 significant digits. PropCIs::orscoreci function uses incremental or decremental search by the factor of 1.001 which gives only about 3 siginicant digits.

Value

The following output will be returned for each strata and common value. There is no standard error.

odd1

odd from the first group, y1/(n1 - y1)

odd2

odd from the second group, y2/(n2 - y2)

OR

odds ratio, odd1/odd2. Point estimate of common OR is calculated with MH weight.

lower

lower confidence limit of OR

upper

upper confidence limit of OR

Author(s)

Kyun-Seop Bae k@acr.kr

References

Miettinen O, Nurminen M. Comparative analysis of two rates. Stat Med 1985;4:213-26

See Also

RDmn1, RRmn1, ORmn1, RDmn, RRmn, RDinv,RRinv, ORinv, ORcmh

Examples

  d1 = matrix(c(25, 339, 28, 335, 23, 370, 40, 364), nrow=2, byrow=TRUE)
  colnames(d1) =  c("y1", "n1", "y2", "n2")
  ORmn(d1)

sasLM documentation built on Sept. 5, 2022, 5:11 p.m.