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#Copyright (c) 2009-2022 Sebastien Bihorel
#All rights reserved.
#
#This file is part of scaRabee.
#
# scaRabee is free software: you can redistribute it and/or modify
# it under the terms of the GNU General Public License as published by
# the Free Software Foundation, either version 3 of the License, or
# (at your option) any later version.
#
# scaRabee is distributed in the hope that it will be useful,
# but WITHOUT ANY WARRANTY; without even the implied warranty of
# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
# GNU General Public License for more details.
#
# You should have received a copy of the GNU General Public License
# along with scaRabee. If not, see <http://www.gnu.org/licenses/>.
#
init.update <- function(a=NULL,
t=NULL,
dosing=NULL,
scale=NULL){
# Set init to a
if (names(a)[1]=='time'){
init <- a[-1]
} else {
init <- a
}
# Subset dosing for event occuring at time t
bolus <- dosing[dosing[,1]==t,,drop=FALSE]
# Update init
if (any(bolus[,3]>0)){
for (i in 1:size(bolus,1)) {
init[bolus[i,2]] <- init[bolus[i,2]] + bolus[i,3]/scale[bolus[i,2]]
}
}
return(init)
}
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