scoper: Spectral Clustering-Based Method for Identifying B Cell Clones

Provides a computational framework for B cell clones identification from adaptive immune receptor repertoire sequencing (AIRR-Seq) datasets. Three models are included (identical, hierarchical, and spectral) that perform clustering among sequences of BCRs/IGs (B cell receptors/immunoglobulins) which share the same V gene, J gene and junction length. Nouri N and Kleinstein SH (2018) <doi: 10.1093/bioinformatics/bty235>. Gupta NT, et al. (2017) <doi: 10.4049/jimmunol.1601850>.

Package details

AuthorNima Nouri [aut, cre], Jason Vander Heiden [ctb], Steven Kleinstein [aut, cph]
MaintainerNima Nouri <[email protected]>
LicenseCC BY-SA 4.0
Package repositoryView on CRAN
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scoper documentation built on Aug. 6, 2019, 1:02 a.m.