scoper-package: scoper: Spectral Clustering-Based Method for Identifying B...

scoper-packageR Documentation

scoper: Spectral Clustering-Based Method for Identifying B Cell Clones

Description

Provides a computational framework for identification of B cell clones from Adaptive Immune Receptor Repertoire sequencing (AIRR-Seq) data. Three main functions are included (identicalClones, hierarchicalClones, and spectralClones) that perform clustering among sequences of BCRs/IGs (B cell receptors/immunoglobulins) which share the same V gene, J gene and junction length. Nouri N and Kleinstein SH (2018) \Sexpr[results=rd]{tools:::Rd_expr_doi(" 10.1093/bioinformatics/bty235")}. Nouri N and Kleinstein SH (2019) \Sexpr[results=rd]{tools:::Rd_expr_doi(" 10.1101/788620")}. Gupta NT, et al. (2017) \Sexpr[results=rd]{tools:::Rd_expr_doi(" 10.4049/jimmunol.1601850")}.

Author(s)

Maintainer: Susanna Marquez susanna.marquez@yale.edu [contributor]

Authors:

Other contributors:

See Also

Useful links:


scoper documentation built on Oct. 6, 2023, 5:09 p.m.