coef_nnls: Compute NNLS coefficients

In scregclust: Reconstructing the Regulatory Programs of Target Genes in scRNA-Seq Data

Compute NNLS coefficients

Description

Computes non-negative least squares coefficients with a matrix right hand side.

Usage

coef_nnls(x, y, eps = 1e-12, max_iter = 1000L)

Arguments

x	Coefficient matrix (p x n matrix)
y	Right hand side (p x m matrix)
eps	Convergence tolerance
max_iter	Maximum number of iterations

Value

A list containing

beta	The estimated coefficient matrix
iterations	A vector containing the number of iterations needed for the i-th column in y in the i-th entry.

References

Duy Khuong Nguyen and Tu Bao Ho. Accelerated anti-lopsided algorithm for nonnegative least squares. International Journal of Data Science and Analytics, 3(1):23–34, 2017.

Adapted from https://github.com/khuongnd/nnls_antilopsided

scregclust documentation built on April 5, 2026, 5:06 p.m.