s2n: simple numerical encoding of a DNA sequence.

In seqinr: Biological Sequences Retrieval and Analysis

simple numerical encoding of a DNA sequence.

Description

By default, if no levels arguments is provided, this function will just code your DNA sequence in integer values following the lexical order (a > c > g > t), that is 0 for "a", 1 for "c", 2 for "g", 3 for "t" and NA for ambiguous bases.

Usage

s2n(seq, levels = s2c("acgt"), base4 = TRUE, forceToLower = TRUE)

Arguments

seq	the sequence as a vector of single chars
levels	allowed char values, by default a, c, g and t
base4	if TRUE the numerical encoding will start at O, if FALSE at 1
forceToLower	if TRUE the sequence is forced to lower case caracters

Value

a vector of integers

Note

The idea of starting numbering at 0 by default is that it enforces a kind of isomorphism between the paste operator on DNA chars and the + operator on integer coding for DNA chars. By this way, you can work either in the char set, either in the integer set, depending on what is more convenient for your purpose, and then switch from one set to the other one as you like.

Author(s)

J.R. Lobry

References

citation("seqinr")

See Also

n2s, factor, unclass

Examples

##
## Example of default behaviour:
##
urndna <- s2c("acgt")
seq <- sample( urndna, 100, replace = TRUE ) ; seq
s2n(seq)
##
## How to deal with RNA:
##
urnrna <- s2c("acgt")
seq <- sample( urnrna, 100, replace = TRUE ) ; seq
s2n(seq)
##
## what happens with unknown characters:
##
urnmess <- c(urndna,"n")
seq <- sample( urnmess, 100, replace = TRUE ) ; seq
s2n(seq)
##
## How to change the encoding for unknown characters:
##
tmp <- s2n(seq) ; tmp[is.na(tmp)] <- -1; tmp
##
## Simple sanity check:
##
stopifnot(all(s2n(s2c("acgt")) == 0:3))

seqinr documentation built on April 6, 2023, 1:10 a.m.