summary.seroincidence: Summarizing fitted seroincidence models

In serocalculator: Estimating Infection Rates from Serological Data

Summarizing fitted seroincidence models

Description

This function is a summary() method for seroincidence objects.

Usage

## S3 method for class 'seroincidence'
summary(object, coverage = 0.95, ...)

Arguments

object	a list(), outputted by stats::nlm() or est.incidence()
coverage	desired confidence interval coverage probability
...	unused

Value

a tibble::tibble() containing the following:

• est.start: the starting guess for incidence rate

• ageCat: the age category we are analyzing

• incidence.rate: the estimated incidence rate, per person year

• CI.lwr: lower limit of confidence interval for incidence rate

• CI.upr: upper limit of confidence interval for incidence rate

• coverage: coverage probability

• log.lik: log-likelihood of the data used in the call to est.incidence(), evaluated at the maximum-likelihood estimate of lambda (i.e., at incidence.rate)

• iterations: the number of iterations used

• antigen_isos: a list of antigen isotypes used in the analysis

• nlm.convergence.code: information about convergence of the likelihood maximization procedure performed by nlm() (see "Value" section of stats::nlm(), component code); codes 3-5 indicate issues:

  • 1: relative gradient is close to zero, current iterate is probably solution.

  • 2: successive iterates within tolerance, current iterate is probably solution.

  • 3: Last global step failed to locate a point lower than x. Either x is an approximate local minimum of the function, the function is too non-linear for this algorithm, or stepmin in est.incidence() (a.k.a., steptol in stats::nlm()) is too large.

  • 4: iteration limit exceeded; increase iterlim.

  • 5: maximum step size stepmax exceeded five consecutive times. Either the function is unbounded below, becomes asymptotic to a finite value from above in some direction or stepmax is too small.

Examples

library(dplyr)

xs_data <-
  sees_pop_data_pk_100

curve <-
  typhoid_curves_nostrat_100 %>%
  filter(antigen_iso %in% c("HlyE_IgA", "HlyE_IgG"))

noise <-
  example_noise_params_pk

est1 <- est.incidence(
  pop_data = xs_data,
  curve_params = curve,
  noise_params = noise,
  antigen_isos = c("HlyE_IgG", "HlyE_IgA")
)

summary(est1)

serocalculator documentation built on April 3, 2025, 7:35 p.m.