Description Usage Arguments Author(s) Examples
Compute matrix of simulated Z scores about expected values of 0 - ie under a null of no association at any SNP
1 | simulated_z_null(snps, freq, nrep = 1)
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snps |
The snps at which we wish to compute the expected Z Score |
freq |
Haplotype frequencies as a data.frame, with column Probability indicating relative frequency in controls. |
nrep |
Number of replicates (simulated vectors of Z scores) under this scenario. Default=1 |
Mary Fortune and Chris Wallace
1 2 3 | freq=fake_freq(nhaps=100,nsnps=5) # fake haplotype frequency data
Z=simulated_z_null(snps=paste0("s",1:5),freq=freq,nrep=3)
Z # no causal variants
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