README.md

snpsettest

R-CMD-check

The goal of ‘snpsettest’ is to provide simple tools that perform set-based association tests (e.g., gene-based association tests) using GWAS (genome-wide association study) summary statistics. A set-based association test in this package is based on the statistical model described in VEGAS (versatile gene-based association study), which combines the effects of a set of SNPs accounting for linkage disequilibrium between markers. This package uses a different approach from the original VEGAS implementation to compute set-level p values more efficiently, as described in here.

To install this package,

install.packages("snpsettest")

Here is a wiki page for tutorial.



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snpsettest documentation built on Sept. 10, 2023, 1:08 a.m.