snpsettest-package: snpsettest: A Set-Based Association Test using GWAS Summary...

In snpsettest: A Set-Based Association Test using GWAS Summary Statistics

snpsettest: A Set-Based Association Test using GWAS Summary Statistics

Description

The goal of 'snpsettest' is to provide simple tools that perform set-based association tests (e.g., gene-based association tests) using GWAS (genome-wide association study) summary statistics. A set-based association test in this package is based on the statistical model described in VEGAS (versatile gene-based association study), which combines the effects of a set of SNPs accounting for linkage disequilibrium between markers. This package uses a different approach from the original VEGAS implementation to compute set-level p values more efficiently, as described in https://github.com/HimesGroup/snpsettest/wiki/Statistical-test-in-snpsettest.

Author(s)

Maintainer: Jaehyun Joo [e-mail]

Authors:

• Blanca Himes [e-mail]

See Also

Useful links:

• https://github.com/HimesGroup/snpsettest

• Report bugs at https://github.com/HimesGroup/snpsettest/issues

snpsettest documentation built on Sept. 10, 2023, 1:08 a.m.