FinemappingConvergence: Simulated Fine-mapping Data with Convergence Problem.

In susieR: Sum of Single Effects Linear Regression

Simulated Fine-mapping Data with Convergence Problem.

Description

Data simulated using real genotypes from 50,000 individuals and 200 SNPs. Two of the SNPs have non-zero effects on the multivariate response. The response data are generated under a linear regression model. The simulated response and the columns of the genotype matrix are centered.

Format

FinemappingConvergence is a list with the following elements:

XtX

Summary statistics computed using the centered and scaled genotype matrix.

Xty

Summary statistics computed using the centered and scaled genotype data, and the centered simulated response.

yty

yty is computed using the centered simulated response.

n

The sample size (50,000).

true_coef

The coefficients used to simulate the responses.

z

z-scores from a simple (single-SNP) linear regression.

See Also

A similar data set with more SNPs is used in the “Refine SuSiE model” vignette.

Examples

data(FinemappingConvergence)

susieR documentation built on March 7, 2023, 6:11 p.m.