predict.poppkmod: Predict method for pkmod objects

In tci: Target Controlled Infusion (TCI)

Predict method for pkmod objects

Description

Predict concentrations from a pkmod object - can be a user defined function

Usage

## S3 method for class 'poppkmod'
predict(object, inf, tms, ...)

Arguments

object	An object with class poppkmod.
inf	A matrix with columns "begin","end","inf_rate" indicating when infusions should be administered. Can be created by 'inf_manual' or 'inf_tci'.
tms	Times at which to calculate predicted concentrations.
...	List or vector of values to be passed on to predict.pkmod.

Value

Matrix of predicted concentrations associated with a poppkmod object and and infusion schedule.

Examples

# dosing schedule
dose <- inf_manual(inf_tms = c(0,0.5,4,4.5,10), inf_rate = c(100,0,80,0,0))
# poppkmod object
data <- data.frame(ID = 1:5, AGE = seq(20,60,by=10), TBW = seq(60,80,by=5),
HGT = seq(150,190,by=10), MALE = c(TRUE,TRUE,FALSE,FALSE,FALSE))
elvd_mod <- poppkmod(data, drug = "ppf", model = "eleveld")
predict(elvd_mod, inf = dose, tms = c(1.5,2.5,3))

tci documentation built on Aug. 15, 2022, 9:09 a.m.