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### Likelihood-hypo-test-KM.R ---
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## Author: Paul Blanche
## Created: Mar 30 2021 (15:10)
## Version:
## Last-Updated: Mar 21 2023 (15:06)
## By: Paul Blanche
## Update #: 69
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##
### Commentary:
## Function to compute likelihood ratio, corresponding to comparison
## between with and without constraint for Kaplan-Meier estimates.
### Change Log:
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##
### Code:
LR.KM <- function(a.1,
a.2,
ni,
di
){
# loglikelihood corresponding to KM1
ll1 <- MyLogLikeKM(a.1,ni,di)
# loglikelihood corresponding to KM2
ll2 <- MyLogLikeKM(a.2,ni,di)
# difference in log-like
LR <- ll2 - ll1
LR
}
LR.test.KM <- function (tstar, pstar, data, mytol=10^(-5)){
# fit with constaint
KM.cont.fit <- KMConstrain(tstar, pstar, data, mytol)
# log-like comparison
myLR01 <- LR.KM(a.1 = KM.cont.fit$a0,
a.2 = KM.cont.fit$ac,
ni = KM.cont.fit$nj,
di = KM.cont.fit$dj
)
# p-value from Chi-square distribution
thepval <- 1-stats::pchisq(-2*myLR01,df=1)
# output
return(list(p=thepval,
Surv.H0=pstar,
Surv.Est=min(KM.cont.fit$S0),
n=KM.cont.fit$n,
TestStat=-2*myLR01))
}
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### Likelihood-hypo-test-KM.R ends here
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