normalizeSensitivity: Normalize the drug sensitivity data

In timma: Target Inhibition Interaction using Maximization and Minimization Averaging

Description

A function to normalize the drug sensitivity data to [0,1]

Usage

normalizeSensitivity(IC50, method = "minMax")

Arguments

IC50	a vector contains the drug sensitivity in the form of IC50.
method	a string to specify the method used to normalize the sensitivity data. If it is "minMax", the sensitivity is scaled by (Max_IC50-IC50)/(Max_IC50-Min_IC50). If it is "logistic", it is scaled by 1/(1+exp(-1/IC50)). If it is "hyperbolic", it is scaled by tanh(1/IC50).

Value

A vector contains the normalized drug sensitivity data.

Author(s)

Jing Tang [e-mail]

Examples

data(tyner_sensitivity)
normalizedSensitivity<-normalizeSensitivity(tyner_sensitivity[,1])

timma documentation built on May 2, 2019, 1:10 p.m.