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Using Gaussian graphical models we propose a novel approach to perform pathway analysis using gene expression. Given the structure of a graph (a pathway) we introduce two statistical tests to compare the mean and the concentration matrices between two groups. Specifically, these tests can be performed on the graph and on its connected components (cliques).
Package details 


Author  Sofia Massa, Gabriele Sales 
Date of publication  20160922 16:51:06 
Maintainer  Gabriele Sales <gabriele.sales@unipd.it> 
License  GPL3 
Version  1.4.6 
Package repository  View on CRAN 
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