Using Gaussian graphical models we propose a novel approach to perform pathway analysis using gene expression. Given the structure of a graph (a pathway) we introduce two statistical tests to compare the mean and the concentration matrices between two groups. Specifically, these tests can be performed on the graph and on its connected components (cliques).
|Author||Sofia Massa, Gabriele Sales|
|Date of publication||2016-09-22 16:51:06|
|Maintainer||Gabriele Sales <[email protected]>|
|Package repository||View on CRAN|
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