summary_tcpl: function to summarize curve fitting results

In toxplot: Batch Processing, Modeling and Visualizing the Dose-Response of High-Throughput Screening Bioassay

Description

function to summarize curve fitting results

Usage

summary_tcpl(tcpl_models, spid_chnm_table = NULL)

Arguments

tcpl_models	the list object returned by 'fit_curve_tcpl' function
spid_chnm_table	a reference table with 'spid' and the corresponding chemical name 'chnm' column, and the CAS number 'casn' column.

Value

a data.frame contains summarized metrics for each chemical (spid)

Examples

## supply models as the essential argument. spid_chnm_table is optional.
demo_md <- fit_curve_tcpl(demo_mc_norm, assay_info =
list(prim_assay = "Primary", toxi_assay = "Cytotox"))
demo_sum <- summary_tcpl(demo_md)


## start from raw data
# define assay
assay_info <- list(prim_assay = "Primary",toxi_assay = "Cytotox")
# data normalization
demo_mc_norm <- normalize_per_plate(demo_mc, nctrl = "DMSO")
# filter out two test chemicals
demo_mc_norm <- dplyr::filter(demo_mc_norm, spid %in% c("TP0001502B05", "TP0001502B01"))
# fit curve with default 20% threshold
demo_md <- fit_curve_tcpl(demo_mc_norm, assay_info)
# obtain summary table
demo_sum <- summary_tcpl(demo_md)

toxplot documentation built on April 3, 2018, 9:04 a.m.