actg315raw: Data from ACTG315 trial of HIV viral load in adults...

In ushr: Understanding Suppression of HIV

Description

Data from the ACTG315 clinical trial of HIV-infected adults undergoing ART. Data are included for 46 individuals, with HIV viral load measurements observed on specific days up to 28 weeks after treatment initiation, and converted to log10 RNA copies/ml. The RNA assay detection threshold was 100 copies/ml. Additional columns include patient identifiers and CD4 T cell counts.

Usage

data(actg315raw)

Format

A data frame with 361 rows and 5 columns:

Obs.No

Row number

Patid

Numerical patient identifier

Day

Time of each observation, in days since treatment initiation

log10.RNA.

HIV viral load measurements, in log10 RNA copies/ml

CD4

CD4 T cell counts, in cells/mm^3

Source

Hulin Wu, Data Sets

References

Lederman et al (1998) JID 178(1), 70–79; Connick et al (2000) JID 181(1), 358–363; Wu and Ding (1999) Biometrics 55(2), 410–418.

Examples

library(dplyr)
data(actg315raw)

actg315 <- actg315raw %>%
    mutate(vl = 10^log10.RNA.) %>%
    select(id = Patid, time = Day, vl)

print(head(actg315))

plot_data(actg315, detection_threshold = 100)

Example output

Loading required package: dplyr

Attaching package: ‘dplyr’

The following objects are masked from ‘package:stats’:

    filter, lag

The following objects are masked from ‘package:base’:

    intersect, setdiff, setequal, union

Loading required package: tidyr
Loading required package: ggplot2
  id time         vl
1  1    0 22998.5259
2  1    2 22998.5259
3  1    7  3400.1651
4  1   16   949.9484
5  1   29   440.0479
6  1   57   129.9870

ushr documentation built on April 22, 2020, 1:05 a.m.