parameters: Parameters

In visit: Vaccine Phase I Design with Simultaneous Evaluation of Immunogenicity and Toxicity

Parameters

Description

Parameters that are shared by multiple functions

Arguments

obs.y	Observed data matrix with l rows and 4 columns. Row k in the matrix represents the observed data from dose level k. The columns are column 1: number of patient with no DLT, no immune response column 2: number of patient with no DLT, immune response column 3: number of patient with DLT, no immune response column 4: number of patient with DLT, immune response
prob.mdl	Option of the probability models: NONPARA: non-parametric+ model NONPARA+: non-parametric model PARA: partially parametric model PARA+: partially parametric+ model Default value is NONPARA. See visit for details.
priors	A class VTPRIOR object created by vtPriorPar for PARA and PARA+ model.
etas	Vector of length 2 representing (p_L, p_U). p_L: lower bound of DLT risk, below which the current dose is considered absolutely safe; p_U: upper bound of DLT risk above which the current dose is considered too toxic
prev.res	Response rate from the next lower dose level, say, l-1. This can be a scalar representing the mean of the response rate E(q^{(l-1)}), or a vector of posterior samples of the response rate q^{(l-1)}. For l=1, this value is set to 0.
dec.cut	Thresholds C_1,C_2,C_3. If the vector length is shorter than 3, it is repeated to have 3 elements. See visit for details.
digits	Digits for print
seed	Random seed
...	Reserved parameters

visit documentation built on Aug. 9, 2023, 5:08 p.m.