vtStan: Call STAN models for MCMC sampling

In visit: Vaccine Phase I Design with Simultaneous Evaluation of Immunogenicity and Toxicity

Call STAN models for MCMC sampling

Description

Call STAN to draw posterior samples of the joint distribution of immunogenicity rate and toxicity risk for parametric and parametric+ model

Usage

vtStan(obs.y, priors, model = 0, iter = 4000, chains = 4,
  warmup = 2000, ...)

Arguments

obs.y	Observed data matrix with l rows and 4 columns. Row k in the matrix represents the observed data from dose level k. The columns are column 1: number of patient with no DLT, no immune response column 2: number of patient with no DLT, immune response column 3: number of patient with DLT, no immune response column 4: number of patient with DLT, immune response
priors	A class VTPRIOR object created by vtPriorPar for PARA and PARA+ model.
model	option of the probability models: 0: parametric model 1: parametric+ model See visit for details.
iter	STAN option: number of iterations
chains	STAN option: number of chains
warmup	STAN option: number of warmup
...	additional parameters for package rstan's sampling method. These options include iter, warmup, thin, algorithm. See rstan::sampling for details.

Value

A rstan object that contains the posterior sampling results

visit documentation built on Aug. 9, 2023, 5:08 p.m.