vpc_opt: Generate a list of options for VPC data generation
In xpose: Diagnostics for Pharmacometric Models

vpc_opt

R Documentation

Generate a list of options for VPC data generation

Description

Provide a list of options to vpc_data function.

Usage

vpc_opt(
  bins = "jenks",
  n_bins = "auto",
  bin_mid = "mean",
  pred_corr = FALSE,
  pred_corr_lower_bnd = 0,
  pi = c(0.025, 0.975),
  ci = c(0.025, 0.975),
  lloq = NULL,
  uloq = NULL,
  rtte = FALSE,
  rtte_calc_diff = TRUE,
  events = NULL,
  kmmc = NULL,
  reverse_prob = FALSE,
  as_percentage = TRUE
)

Arguments

`bins`	Binning method, can be one of 'density', 'time', 'data', 'none', or one of the approaches available in `classInterval()` such as 'jenks' (default), 'pretty', or a numeric vector specifying the bin separators.
`n_bins`	When using the 'auto' binning method, what number of bins to aim for.
`bin_mid`	Specify how to is the mid bin value calculated, can be either 'mean' for the mean of all timepoints (default) or 'middle' to use the average of the bin boundaries.
`pred_corr`	Option reserved to continuous VPC. Logical, should a prediction correction (pcVPC) of the data be used.
`pred_corr_lower_bnd`	Option reserved to continuous VPC. Lower bound for the prediction-correction.
`pi`	Option reserved to continuous VPC. Simulated prediction interval to plot. Default is c(0.05, 0.95).
`ci`	Confidence interval around the percentiles to plot. Default is c(0.05, 0.95)
`lloq`	Number or NULL indicating lower limit of quantification. Default is NULL.
`uloq`	Number or NULL indicating upper limit of quantification. Default is NULL.
`rtte`	Option reserved to time-to-event VPC. Is the data repeated time-to-event (RTTE) `TRUE` or single time-to-event (TTE) `FALSE`.
`rtte_calc_diff`	Option reserved to time-to-event VPC. Should the time be recalculated? When simulating in NONMEM, you will probably need to set this to `TRUE` to recalculate the TIME to the relative time between events (unless you output the time difference between events and specify that as independent variable in the index.
`events`	Option reserved to time-to-event VPC. Numeric vector describing which events to show a VPC for when repeated TTE data, e.g. c(1:4). Default is `NULL`, which shows all events.
`kmmc`	Option reserved to time-to-event VPC. Either NULL for regular TTE VPC (default), or a variable name for a KMMC plot (e.g. 'WT').
`reverse_prob`	Option reserved to time-to-event VPC. Should the probability be reversed (i.e. plot 1-probability).
`as_percentage`	Should the Y-scale be in percent (0-100) `TRUE` (default), or standard (0-1) `FALSE`.