CenterForStatistics-UGent/SPsimSeq: Semi-parametric simulation tool for bulk and single-cell RNA sequencing data

SPsimSeq uses a specially designed exponential family for density estimation to constructs the distribution of gene expression levels from a given real RNA sequencing data (single-cell or bulk), and subsequently simulates a new dataset from the estimated marginal distributions using Gaussian-copulas to retain the dependence between genes. It allows simulation of multiple groups and batches with any required sample size and library size.

Getting started

Package details

Bioconductor views DNASeq GeneExpression RNASeq Sequencing SingleCell
Maintainer
LicenseGPL-2
Version0.99.13
URL https://github.com/CenterForStatistics-UGent/SPsimSeq
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("CenterForStatistics-UGent/SPsimSeq")
CenterForStatistics-UGent/SPsimSeq documentation built on May 23, 2020, 2:38 p.m.