CshlSiepelLab/DENR: Deconvolution of Expression for Nascent RNA Sequencing Data

DENR is a new computational method built to quantify the abundance of distinct precursor RNAs based on nascent RNA sequencing data. It models the nascent RNA read counts at each locus as a mixture of user-provided isoforms. The performance of the baseline algorithm is enhanced by the use of machine-learning predictions of transcription start sites (TSSs) and an adjustment for the typical "shape profile"" of read counts along a transcription unit.

Getting started

Package details

Bioconductor views Software StatisticalMethod Transcriptomics
LicenseGPL (>=2)
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
CshlSiepelLab/DENR documentation built on March 19, 2021, 8:55 p.m.