sim.cell.expr: sim.cell.expr

In ERGlass/lrcde.dev: Linear Regression Cell Type-Specific Differential Expression Power Analysis

Description

Called from sim_driver_script.

Usage

sim.cell.expr(num.cells, num.genes = 5000, base.expr = 5, diff.expr = 1,
  prop.2.fold = 0.5, cell.p)

Arguments

num.cells	Number of cell types to simulate.
num.genes	Number of genomic sites to simulate.
base.expr	Control group expression level to simulate at the cell type-specific level.
diff.expr	Absolute difference between control group and cases group to simulate at the cell type-specific level.
prop.2.fold	Proportion of simulate genomic sites to "fold" or alter between controls and cases.
cell.p	Number of cell type to alter between controls and cases for simulation purposes.

Value

List containing group-wise matrix of simulated cell type-specific expressions (rbinded as controls and cases.) and "truth" vector of 0's and 1's indicating which genomic sites have been altered for cell type p.

Author(s)

Edmund R Glass, [e-mail]

References

https://github.com/ERGlass/lrcde.dev

Examples

sim.cell.expr(num.cells.2.simulate, num.genes.2.simulate, base.expression, difference.2.simulate, proportion.of.sim.genes.2.fold, cell.2.modify )

ERGlass/lrcde.dev documentation built on May 6, 2019, 3:09 p.m.