README.md

In GreenwoodLab/RVPedigree: Methods for Family-Based Rare-Variant Genetic Association Tests

RVPedigree

An R package which is a collection of the five region-based rare-variant genetic association tests. The following tests are currently implemented: ASKAT, ASKAT-Normalized, VC-C1, VC-C2 and VC-C3.

Installation

You first need to install the R package snpStats from Bioconductor:

## try http:// if https:// URLs are not supported
source("https://bioconductor.org/biocLite.R")
biocLite("snpStats")

You can then install the RVPedigree package from GitHub using the devtools package:

library(devtools)
devtools::install_github('GreenwoodLab/RVPedigree', build_vignettes = TRUE)

Usage

Please see the included vignette to see how the functions included in this package can be used. From within R use the following command:

vignette("vignette", package = "RVPedigree")

References

A BibTeX entry for LaTeX users:

@article{lakhal2015rare, title={A rare variant association test in family-based designs and non-normal quantitative traits}, author={Lakhal-Chaieb, Lajmi and Oualkacha, Karim and Richards, Brent J and Greenwood, Celia MT}, journal={Statistics in medicine}, year={2015}, publisher={Wiley Online Library} }

GreenwoodLab/RVPedigree documentation built on May 6, 2019, 6:33 p.m.